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Protease: The Importance of Protein Digestion

Protein is one of the three major food groups needed for proper nutrition. Protease is the digestive enzyme needed to digest protein.


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High protease supports circulation, immunity, and healthy elimination






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Every animal, including humans, must have an adequate source of protein in order to grow or maintain itself. Proteins, which yield amino acids, are the fundamental structural element of every cell in the body.  Specific proteins are now recognized as the functional elements in certain specialized cells, glandular secretions, enzymes and hormones.

Proteins, which are among the most complex organic compounds found in nature, are made up of nitrogen containing compounds known as amino acids.  During the digestion of proteins, hydrochloric acid and proteolytic enzymes break down the intact protein molecule into amino acids which are then absorbed through the intestinal wall. If proteins are not properly broken down before they are absorbed, various health consequences may occur.
Assuring optimal protein digestion and proper blood flow is necessary for effective nutrient delivery, a healthy immune response, and detoxification. Protease enzymes are therefore a must. Our PureZyme formula is uniquely designed with high protease to promote systemic balance.*

The Importance of Proteases

Proteases refers to a group of enzymes whose catalytic function is to hydrolyze (breakdown) proteins. They are also called proteolytic enzymes or systemic enzymes.

Proteolytic enzymes are very important in digestion as they breakdown the the peptide bonds in the protein foods to liberate the amino acids needed by the body. Additionally, proteolytic enzymes have been used for a long time in various forms of therapy. Their use in medicine is notable based on several clinical studies indicating their benefits in oncology, inflammatory conditions, blood rheology control, and immune regulation. Read more about proteases in enzyme therapy.

Protease is able to hydrolyze almost all proteins as long as they are not components of living cells.  Normal living cells are protected against lysis by the inhibitor mechanism. 

Parasites, fungal forms, and bacteria are protein.  Viruses are cell parasites consisting of nucleic acids covered by a protein film.  Enzymes can break down undigested protein, cellular debris, and toxins in the blood, sparing the immune system this task.  The immune system can then concentrate its full action on the bacterial or parasitic invasion.

How Protease Deficiency Can Affect Your Health:

  • Acidity is created through the digestion of protein. Therefore a protease deficiency results in an alkaline excess in the blood.  This alkaline environment can cause anxiety and insomnia. 
  • In addition, since protein is required to carry protein-bound calcium in the blood, a protease deficiency lays the foundation for arthritis, osteoporosis and other calcium-deficient diseases.
  • Because protein is converted to glucose upon demand, inadequate protein digestion leads to hypoglycemia, resulting in moodiness, mood swings and irritability.
  • Protease also has an ability to digest unwanted debris in the blood including certain bacteria and viruses. Therefore, protease deficient people are immune compromised, making them susceptible to bacterial, viral and yeast infections and a general decrease in immunity

For information on how fats (lipids) are digested, see Lipase.

For information on how carbohydrates are digested, see Amylase.

New to Digestive Enzymes?

Read why taking Digestive Enzyme Supplements is so important for optimum health!

Want to know more about Digestive Enzymes? See our Enzyme FAQs.

Wondering which digestive enzymes to take? See our full list of suggestions!

Try one of these top sellers for a full blend of all the digestive enzymes needed to maximize your digestion!

oxi digest pure carbo

Digest 90
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120 caps $31.95



240 caps $53.95


120 capsules $39.95


60 capsules $44.95




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Enzyme Essentials, LLC

* Statements have not been evaluated by the Food and Drug Administration (FDA). Products not intended to diagnose, treat, cure, or prevent any disease.

The information contained here is for reference only and is not intended to diagnose disease or prescribe treatment. The information contained herein is in no way to be considered a substitute for consultation with a health care professional. Furthermore, this information is for the private use of our clients and is not to be used publicly, reproduced, or distributed without the written consent of Enzyme Essentials, LLC

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