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PureZyme
Protease assists in the digestion of protein and increases the production of energy. Protease is also known to act as a scavenger of oxidized and damaged proteins, is active in helping to eliminate blood toxins, modulate the immune system, addresses hormonal imbalances, speeds wound and tissue repair, helps to chelate heavy metals and removes their toxins. PureZyme is part of the E-Club Enhanced Enzyme Nutrition System. Due to the extensive benefits of the hydrolytic enzyme Protease, we have provided more in-depth background on this product. For more information please see: Proteases In Enzyme Therapy. New Article! How PureZyme can help with Preventing Periodontal Disease
Click Here to view your Shopping Cart Each capsule of PureZyme provides:
Other ingredients: Vegetarian capsule (cellulose and water) Learn more about digestive enzyme labeling and measurement standards. Recommended Usage for PureZyme: Take at least 2 capsules ON AN EMPTY STOMACH between meals or first thing in the morning and/or before bed or on advice of health care provider. The formulation is best used on an empty stomach (usually 1 hour before or 2 hours after eating) in order to optimize the amount of protease absorbed into the blood stream. Taking PureZyme on an empty stomach is important. Proteases break down (digests) protein. If food is present in the stomach, the ingested (protease) enzymes will tend to stop in the stomach to digest that food. If the stomach is empty, the proteases will advance to the blood system where it acts to attack and breakdown protein invaders which are not part of the natural body. The results of PureZyme have been seen in the blood within ten minutes after ingestion.
Contraindications PureZyme contains protease which can cause a burning sensation if you have any of the following conditions: Gastritis, Gastric Ulcer, Duodenal Ulcers, Esophage Ulcers. GastroZyme may be used until these conditions are alleviated, then you can begin to take products containing proteases. There is no protease in GastroZyme. See the product information on GastroZyme for more information on this formulation.
Component Benefits Protease The benefits of oral proteases may include:
NOTE: Proteases have been shown to have powerful physiological actions. For more detailed information on the beneficial effects of proteases go to Proteases In Enzyme Therapy. Calcium
Citrate
PureZyme contains proprietary, highly concentrated proteolytic enzymes from Aspergillus oryzae. Proteolytic enzyme supplements taken by mouth (on an empty stomach) have been shown to be absorbed in substantial quantities into the blood, to bind to serum proteins, especially alpha 2-macroglobulin (a2M), and to be delivered to sites of immune function. One of the best-established functions served by Aspergillus protease is in the maintenance of normal blood flow by breaking down blood clots (fibrinolysis). Years of clinical experience have shown that toxins are also removed from the blood, perhaps as a result of an overall improvement in blood flow. There is a change in the conformation of a2M when protease is bound to it, which is evident, as an increase in mobility in polyacrylamide gel electrophoresis, referred to as a shift from the "slow" to the "fast" form. Accompanying this shift is a dramatic increase in the tendency of activated macrophages, fibroblasts and hepatocytes to bind the a2M complex. Moreover, a2M complexes also exhibit an increased binding of several very important cytokines (hormone-like molecules which have a powerful influence on immune cells) such as transforming growth factor-beta (TGF-b) and tumor necrosis factor-alpha (TNF-a). By modulating, and potentially delivering such cytokines to sites of immune system activity, the a2M/protease complexes, which result from oral protease supplementation, have a powerful immune-strengthening effect. Years of clinical experience have led to the conclusion that hormonal imbalances may be helped by oral protease supplementation. For instance, in cases of gastrin deficiency, the secretion of acid and pepsin may be impaired resulting in poor protein digestion and other digestive disorders. Oral protease supplementation will ensure protein digestion and proper nutrition. There is a well-recognized linkage between enzyme secretion/regulation, the neuroendocrine, and the immune systems. It may be that correcting hormonal imbalances result in strengthening and balancing the immune system. Glomerulonephritis: In this disease there is a build up of protein in the basement membrane of the glomeruli of the kidneys. Fluids must pass through this basement membrane in the initial phase of the filtration of the blood by the kidneys. Recent research using an animal model of this disease "lends further support to the concept that enzymes capable of degrading immune complexes in situ can ameliorate glomerulonephritis". Tissue repair, or wound healing, is usually divided into three phases: Inflammatory, which is characterized by platelet accumulation, coagulation and leukocyte migration. Proliferate, which is characterized by re-epithelialization, angiogenesis, fibroplasia and wound contraction. Remodeling, which takes place over a period of months, in which the dermis responds to injury with the production of collagen and matrix proteins and then returns to its pre-injury structure. Research has shown that these processes are regulated by various cytokines. As discussed above, oral protease supplementation leads to the formation of activated a2M, which significantly modulates tissue cytokines. Heavy metals, such as lead (Pb) and mercury (Hg) exert their poisoning effect by binding to ionizable or sulfhydryl groups of proteins, including vital enzymes. Once they bind to an essential functional protein, such as an enzyme, they denature and/or inhibit it. This interaction of heavy metals to proteins can lead to degenerating diseases, nerve damage or even death. It should be noted that protease when taken on an empty stomach is readily taken up into the mucosa cells of the intestine and passed into blood circulation. Clinical observations have noted that upon high intake of proteases, heavy metal concentrations have been significantly decreased in the blood. This may be due to the binding of these toxic substances with the supplemental protease enzymes, facilitating their removal through the kidneys or intestine, thus avoiding a life-threatening situation of poisoning. The result may spare other vital proteins, including metabolic enzymes, in the body. Scavenger of Oxidated and Damaged Protein Oxidative reactions generate free radical damage to various molecules including proteins. Free radicals have been implicated in accelerating the aging process as well as several diseases, including diabetes, arteriosclerosis, and neurodegenerative conditions. Under proper conditions of nutrition and adequate activity of antioxidant enzymes, the free radical damage is minimized. However, in many instances, the body is overwhelmed by the load of pro-oxidants (free radical generating molecules), resulting in oxidative stress conditions. One consequence of oxidative stress is the formation of oxidized proteins. Oxidized proteins often lose their function (become inactive), and undergo unfolding or conformational change of their structure which enhances their susceptibility to proteolysis. For instance, oxidized proteins in blood or extra cellular fluid, include hormones, immune system proteins, transport proteins, and other proteins needed at various cellular locations. As these oxidized proteins lose their biological function, they may not carry out the cellular tasks and biochemical reactions they are meant to perform. For instance, an oxidized hormone may not be able to attach to its receptor on the cell surface; an oxidized enzyme may not perform its activity; an oxidized antibody molecule will not bind to its antigen. Oxidative reactions occur in a cascade manner. Therefore, oxidation of one protein may lead to further oxidation reactions within the same molecule and/or other molecules, which amplify the damaging effect. Thus, any oxidation of a protein if not corrected may result in impairment of biochemical functions of vital importance to the cellular viability. In order to avoid the cascade effect, oxidized proteins may be reduced by an antioxidant or removed by proteolysis. Several studies have indicated that oral proteases bound to the a2-macroglobulin hydrolyze immune complexes, proteinaceous debris, damaged proteins, and acute phase plasma proteins in the blood stream. It is suggested that oral proteases may help hydrolyze and remove extracellular proteins damaged by free radicals which are especially susceptible to proteolysis, as mentioned above. PureZyme, as a formulation of proteases that have a wider range of pH, is suggested as a digestive aid. One of its many attributes is its assistance to this problem. Loss of bone density is characterized by progressive breaking of the bone tissue which releases calcium, and also by an inefficient rate of synthesis on the part of the osteoblast cells. The cells responsible for the degradation of the bone are the osteoclasts. The rate of synthesis by the osteoblasts and the rate of breakdown by the osteoclasts are influenced by good nutrition. This includes adequate supplies of calcium and its uptake, hormone levels, digestive disorders, and other factors. A program to maintain optimum bone density should provide amino acids, absorbable calcium, and mucopolysaccharides. That is what PureZyme provides and enhances. The beneficial effect of PureZyme in helping alleviate bone loss is attributed to:
As nutrition, i.e., digestion and uptake of nutrients, is improved, the body can synthesize the hormones needed for increased anabolism of the skeletal system. The inclusion of calcium in the form of calcium citrate, along with the proteases, makes PureZyme a good product to provide amino acids and facilitate absorption of calcium. |
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Copyright
2007 The information contained here is for reference only and is not intended to diagnose disease or prescribe treatment. The information contained herein is in no way to be considered a substitute for consultation with a health care professional. Furthermore, this information is for the private use of our clients and is not to be used publicly, reproduced, or distributed without the written consent of Enzyme Essentials, LLC
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